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Combo-pilling may be the newest fad or better yet the newest ahead under scrutiny and so it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular will be the fact that at the time of right now there are no long term prescription weight loss supplements that have been authorized by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be licensed by the FDA. Seizures certainly are a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug could also raise blood pressure levels and heartrate, and must not be used in people with a history of cardiac event or stroke in the last six months. 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